Overview
Molecubes designs user-friendly, modular molecular imaging solutions (X-CUBE, γ-CUBE, β-CUBE) for research labs, making preclinical imaging more accessible. Their benchtop systems are applicable across oncology, drug development, neurology, cardiology, and other research fields.
Key people
In the news
- Last week, CUBES Application Scientist Etlir Xharra attended EANM 2026 in the beautiful Vienna, with a notebook full of new findings, a reading list that somehow got even longer, and a good excuse to try his way through plenty of Wiener Schnitzel and Apfelstrudel. 😅 🔬 A few themes from this year's meeting stood out: • Theranostics: Ac-225, Pb-212 and Tb-161, and how they compare with Lu-177 in targeted radionuclide therapy. • New targets: FAP, TROP2, CD70 and Nectin-4, among the approaches being explored alongside PSMA. •
- The CUBES headquarter was busy with an international visit last week 🔧 Service engineers from our Bruker BioSpin teams around the world flew in for a week of hands-on training including training on the next-generation SPECT Ɣ-CUBE! A big part of the week went to the new hardware the team developed specifically for the Ɣ-CUBE: ◻️ The UltraLofthole collimator, which uses elliptical apertures in a staggered layout instead of conventional circular pinholes ◻️ The redesigned shielding around the detectors and bore, designed for
- Animal welfare and good imaging data aren’t competing goals. We’re returning to the AALAS annual national meeting this year to talk about animal welfare in preclinical imaging 🔬 📍 77th AALAS National Meeting, October 25–29, 2026, at the George R. Brown Convention Center in Houston, TX 👋 Connect with Angela Mills , Lindsay Andrews, CPIA, ALAT and Dwayne Dexter, PhD at Spectral Instruments Imaging to learn how we can help you advance your imaging studies while keeping high animal care standards. Working with SPF or
- Can dynamic imaging throughput be increased using multi-animal acquisition? 🔬 This week we show full-body dynamic SPECT imaging of three mice at the same time of Tc99m-mebrofenin. The total acquisition was 45 minutes with activities of 18.9 –19.6 MBq at scan start. Mebrofenin is a hepatobiliary tracer. It is taken up by the liver, then cleared through the bile ducts into the gallbladder and intestine like we can see on the dynamic image. Multi-animal imaging on the new-generation SPECT Ɣ-CUBE enables both static and dynamic
- Can a single imaging platform support the growing diversity of radionuclides? Our new whitepaper on the next-generation SPECT Ɣ-CUBE is out! 🎉 📄 Download it here: https://lnkd.in/efZCK2EH It includes a wide range of validation experiments on the next next-generation SPECT Ɣ-CUBE, including experiments with High-energy radionuclides, multiple-isotope experiments and High throughput data: → Results using isotopes like 225Ac, 131I and 18F-FDG → Time-activity curves from dynamic SPECT experiments using 99mTc-tetrofosmin → Low-dose
- Last opportunity to join the Theranostics Spotlight Series at EANM 2026 👉 Check the full presentation program: https://lnkd.in/evzw2kde Meet the scientists and product experts behind SPECT Y-CUBE, and pmod 4.6 and bring your questions: ❓ How do you quantify I-131 or Ac-225 reliably in vivo? ❓ What does dynamic SPECT with short time frames mean for kinetic modeling? ❓ Can SPECT support my dosimetry workflow? Get your answers at Bruker booth #301!
- Let’s talk theranostics at #EANM2026 ! Are you working on theranostic approaches, or other challenging preclinical imaging studies? Come visit the Bruker booth (301) at EANM and meet the team! We’d love to hear about your research and where you want to take your studies next. Check out our 𝗼𝗻-𝗯𝗼𝗼𝘁𝗵 𝗽𝗿𝗲𝘀𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻𝘀 happening throughout EANM, where we’ll talk about our 𝗻𝗲𝘄 𝗦𝗣𝗘𝗖𝗧 𝗖𝗨𝗕𝗘 𝗳𝗼𝗿 𝗧𝗵𝗲𝗿𝗮𝗻𝗼𝘀𝘁𝗶𝗰𝘀, and the 𝗕𝗿𝘂𝗸𝗲𝗿 𝗣𝗖𝗜 𝘀𝗼𝗳𝘁𝘄𝗮𝗿𝗲 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻𝘀. 👉 Check the full
- Biology moves fast. Can the SPECT Ɣ-CUBE keep up? The high temporal resolution of the SPECT Ɣ-CUBE enables kinetic modeling and a better understanding of biological processes. 🔬This week we present dynamic SPECT: time-activity curves of Tc99m-tetrofosmin in a mouse on the next-generation SPECT Ɣ-CUBE. The acquisition was 30 minutes, with frames as short as 13 seconds, with the potential to go as low as 5 seconds. Tetrofosmin is a myocardial perfusion tracer, most of it accumulating to the kidneys and liver, as shown by the
Alumni
- PBert VandeghinsteSenior Engineer and Founder
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